Good Laboratory Practice

Technical note:Beyond Good Laboratory Practice

Good Laboratory Practice for optimization research

Graham Kendall*, Ruibin Bai, Jacek Błazewicz, Patrick De Causmaecker, Michel Gendreau, Robert John, Jiawei Li, Barry McCollum, Erwin Pesch, Rong Qu, Nasser Sabar, Greet Vanden Berghe and Angelina Yee University of Nottingham, Nottingham, UK; University of Nottingham Malaysia Campus, Semenyih, Malaysia; University of Nottingham Ningbo, Ningbo, China; Poznan University of Technology, Poznan, Pola...

Judging the Data: Peer Review versus Good Laboratory Practice Standards

When it comes to assessing the quality of toxicologic data to develop policy decisions, should regulators rely on journal peer review or on Good Laboratory Practice (GLP) standards? Authors of a review comparing the two conclude that the answer is neither. Instead, they propose that regulators need a well-defined scheme in which the best elements of both processes enable data to be weighed and ...

Good laboratory practice: preventing introduction of bias at the bench.

BACKGROUND AND PURPOSE As a research community, we have failed to demonstrate that drugs which show substantial efficacy in animal models of cerebral ischemia can also improve outcome in human stroke. Summary of Review- Accumulating evidence suggests this may be due, at least in part, to problems in the design, conduct and reporting of animal experiments which create a systematic bias resulting...

Good laboratory practice 30 years on: challenges for industry.

The principles of good laboratory practice (GLP) have undergone little change since they were established 30 years ago. Conversely, there have been huge advances in science and technology during this time. Test facilities (TF) have been challenged to utilise these advancements and thus enhance the quality of their programmes of non-clinical safety testing. As a consequence, practices are very d...